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Metadata
DOID DOID:12603
Name acute leukemia
Definition A leukemia that occurs when a hematopoietic stem cell undergoes malignant transformation into a primitive, undifferentiated cell with abnormal longevity. These lymphocytes (acute lymphocytic leukemia [ALL]) or myeloid cells (acute myelocytic leukemia [AML]) proliferate abnormally, replacing normal marrow tissue and hematopoietic cells and inducing anemia, thrombocytopenia, and granulocytopenia.
http://en.wikipedia.org/wiki/Acute_leukemia, http://www.bloodjournal.org/content/bloodjournal/128/3/462.full.pdf, http://www.merck.com/mmpe/sec11/ch142/ch142b.html
Xrefs

ICD10CM:C95.0

ICD10CM:C95.00

ICD9CM:208.0

NCI2004_11_17:C9298

NCI:C9300

OMIM:308960

SNOMEDCT_US_2018_03_01:24072005

SNOMEDCT_US_2018_03_01:91855006

UMLS_CUI:C0085669

UMLS_CUI:C1378511

Alternateids

DOID:12621

Subsets

NCIthesaurus

Synonyms

Stem cell leukaemia [EXACT]

Stem cell Leukemia [EXACT]

Relationships

is_a leukemia

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