| Metadata | |
|---|---|
| ID | DOID:0050214 |
| Name | Lambert-Eaton myasthenic syndrome |
| Definition | A neuromuscular junction disease that is characterized by an abnormality of acetylcholine (ACh) release at the neuromuscular junction which results from an autoimmune attack against voltage-gated calcium channels (VGCC) on the presynaptic motor nerve terminal. http://en.wikipedia.org/wiki/Lambert%E2%80%93Eaton_myasthenic_syndrome |
| Xrefs |
SNOMEDCT_US_2023_03_01:230688006 |
| Subsets |
NCIthesaurus |
| Synonyms |
Eaton-Lambert syndrome [EXACT] Lambert-Eaton syndrome [EXACT] LEMS [EXACT] |
| Parent Relationships |
is_a neuromuscular junction disease |
| Subclass Logical Relationships |
has phenotype some Abnormal circulating immunoglobulin concentration |