Metadata | |
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ID | DOID:0060015 |
Name | interleukin-7 receptor alpha deficiency |
Definition | A severe combined immunodeficiency that results from defective IL7R expression causes T-B+NK+ SCID. Loss of IL-7R function leads to the loss of an antiapoptotic signal, resulting in a loss of T-cell selection in thymus. https://www.ncbi.nlm.nih.gov/pubmed/15661025 |
Synonyms |
IL-7R [EXACT] |
Parent Relationships |