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Metadata
ID	DOID:0060018
Name	CD3gamma deficiency
Definition	A severe combined immunodeficiency that has_material_basis_in autosomal recessive mutations in the gene coding for T-cell surface glycoprotein CD3gamma chain precursors. Patients with CD3gamma deficiency have a severe defect in the expression of the T-cell receptor CD3-complex. Affected patients have decreased T-cell numbers and function; B cells are variably affected. https://www.ncbi.nlm.nih.gov/pubmed/16264327
Parent Relationships	is_a severe combined immunodeficiency is_a autosomal recessive disease