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Metadata
ID DOID:0061225
Name interleukin-1 receptor antagonist deficiency
Definition An autoinflammatory disease characterized by joint swelling and pain, pustular rash, oral mucosal lesions, and fetal distress that has_material_basis_in homozygous mutation in the IL1RN gene on chromosome 2q14.
https://www.nomidalliance.org/dira.php, https://pubmed.ncbi.nlm.nih.gov/19494218/
Xrefs

GARD:10516

MIM:612852

ORDO:210115

SKOS

exactMatch MIM:612852

exactMatch ORDO:210115

exactMatch GARD:10516

Subsets

DO_rare_slim

Synonyms

Autoinflammatory disease due to interleukin-1 receptor antagonist deficiency [EXACT]

chronic recurrent multifocal osteomyelitis-2 with periostitis and pustulosis [EXACT]

immunoglobulin heavy chain deletion [EXACT]

Sterile multifocal osteomyelitis with periostitis and pustulosis [EXACT]

Parent Relationships

is_a autoinflammatory disease

is_a autosomal recessive disease

Subclass Logical Relationships

has material basis in some autosomal recessive inheritance

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