| Metadata | |
|---|---|
| ID | DOID:0070722 |
| PURL | http://purl.obolibrary.org/obo/DOID_0070722 Copy |
| Name | adult-onset leukoencephalopathy without lacunae |
| Definition | A leukodystrophy characterized by a diffuse vascular leukoencephalopathy without lacunar infarct and a hippocampal type of memory defect with onset in the sixth to seventh decade that has_material_basis_in heterozygous mutation in the LAMB1 gene on chromosome 7q31. https://pubmed.ncbi.nlm.nih.gov/34606115/ |
| Xrefs | |
| SKOS |
exactMatch MIM:621424 |
| Subsets |
DO_rare_slim |
| Synonyms |
LUCAO [EXACT] |
| Parent Relationships |
is_a autosomal dominant disease is_a leukodystrophy |
| Subclass Logical Relationships |
has material basis in some autosomal dominant inheritance disease has basis in some gene |