| Metadata | |
|---|---|
| ID | DOID:0080796 |
| PURL | http://purl.obolibrary.org/obo/DOID_0080796 Copy |
| Name | core binding factor acute myeloid leukemia |
| Definition | An acute myeloid leukemia that is characterized by the presence of t(8;21)(q22;q22) or inv(16)(p13q22)/t(16;16)(p13;q22). These cytogenetic abnormalities result in disruption of the transcription factor CBF, which is a regulator of normal hematopoiesis. https://pubmed.ncbi.nlm.nih.gov/26980726/ |
| Xrefs | |
| Subsets |
DO_cancer_slim NCIthesaurus |
| Parent Relationships |