| Metadata | |
|---|---|
| ID | DOID:0080826 |
| Name | nocturnal asthma |
| Definition | A chronic asthma that is characterized by significant decline in pulmonary function and increase of airway inflammation at night. During sleep, recumbent posture causes a reduction in the lung volumes, respiratory muscle tone, and lung compliance. The overnight physiological abnormalities include: increased airway inflammation and decreased steroid responsiveness, increased pulmonary capillary blood volume, functional differences in blood/air volume ratios and mechanical coupling of the parenchyma to the airways. https://pubmed.ncbi.nlm.nih.gov/17571537/, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197640/ |
| Parent Relationships |
is_a chronic asthma |