| Metadata | |
|---|---|
| ID | DOID:0081064 |
| PURL | http://purl.obolibrary.org/obo/DOID_0081064 Copy |
| Name | BN2 diffuse large B-cell lymphoma |
| Definition | A diffuse large B-cell lymphoma that is categorized as BN2 with high probability by the LymphGen algorithm. This is based on a combination of genetic features and BN2 DLBCLs often, but do not always, have a translocation involving the BCL6 locus and/or some combination of mutations affecting NOTCH2, TNFAIP3, BCL10 and UBE2A. This subgroup also commonly has mutations due to aberrant somatic hypermutation affecting CD70, which can be coding or non-coding. https://pubmed.ncbi.nlm.nih.gov/29641966/, https://www.ncbi.nlm.nih.gov/articles/PMC8459709/ |
| Xrefs | |
| Subsets |
DO_cancer_slim NCIthesaurus |
| Synonyms |
BN2 DLBCL [EXACT] |
| Parent Relationships |