| Metadata | |
|---|---|
| ID | DOID:0081066 |
| PURL | http://purl.obolibrary.org/obo/DOID_0081066 Copy |
| Name | MCD diffuse large B-cell lymphoma |
| Definition | A diffuse large B-cell lymphoma that is categorized as MCD with high probability by the LymphGen algorithm. This is based on a combination of genetic features and MCD DLBCLs often, but do not always, have the most common hot spot mutation in MYD88 (L265P) and/or activating mutations in CD79B. This subgroup also commonly has mutations due to aberrant somatic hypermutation affecting PIM1 and/or ETV6, which can be coding or non-coding. https://pubmed.ncbi.nlm.nih.gov/29641966/, https://www.ncbi.nlm.nih.gov/articles/PMC8459709/ |
| Xrefs | |
| Subsets |
DO_cancer_slim NCIthesaurus |
| Synonyms |
MCD DLBCL [EXACT] |
| Parent Relationships |