| Metadata | |
|---|---|
| ID | DOID:0081076 |
| Name | blastic plasmacytoid dendritic cell neoplasm |
| Definition | An acute leukemia that is derived from the precursors of plasmacytoid dendritic cells, with a high frequency of cutaneous and bone marrow involvement and leukemic dissemination. Skin lesions appearing on the arms, legs, face and neck are the most common BPDCN symptom. Other symptoms include low counts of healthy blood cells and swollen lymph nodes. https://pubmed.ncbi.nlm.nih.gov/31972688/, https://www.lls.org/leukemia/blastic-plasmacytoid-dendritic-cell-neoplasm, https://pubmed.ncbi.nlm.nih.gov/30350260/ |
| Xrefs | |
| Subsets |
NCIthesaurus |
| Synonyms |
Agranular CD4+ CD56+ Hematodermic Neoplasm/Tumor [EXACT] Agranular CD4+ Natural Killer Cell Leukemia [EXACT] Blastic Natural Killer Leukemia/Lymphoma [EXACT] Blastic NK-Cell Lymphoma [EXACT] CD4+/CD56+ Hematodermic Neoplasm [EXACT] natural killer (NK) cell leukemia/lymphoma [EXACT] |
| Parent Relationships |
is_a acute leukemia |
| Subclass Logical Relationships |
has symptom some lymphadenopathy has symptom some skin lesion |