| Metadata | |
|---|---|
| ID | DOID:0081250 |
| Name | CIC-rearranged sarcoma |
| Definition | An EWSERI-negative small round cell tumor that is characterized by a recurrent translocation involving the CIC gene on chromosome 19 and either DUX4 gene on chromosome 4 or DUX4L gene on chromosome 10. The translocation results in either CIC-DUX4, t(4;19)(q35;q13) or CIC-DUX4L, t(10;19)(q26;q13) fusions. https://pubmed.ncbi.nlm.nih.gov/31288305/, https://pubmed.ncbi.nlm.nih.gov/32796172/, https://pubmed.ncbi.nlm.nih.gov/33680459/ |
| Xrefs |
ICDO:9367/3 |
| Subsets |
DO_cancer_slim NCIthesaurus |
| Synonyms |
Capicua transcriptional repressor (CIC)-rearranged sarcoma [EXACT] |
| Parent Relationships |