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Metadata
ID DOID:0110926
Name congenital myopathy 4B
Definition A congenital myopathy that is characterized by the onset of muscle weakness in infancy or early childhood and that has_material_basis_in homozygous or compound heterozygous mutation in the alpha-tropomyosin-3 gene (TPM3) on chromosome 1q21.
https://www.ncbi.nlm.nih.gov/pubmed/24095155, https://www.ncbi.nlm.nih.gov/pubmed/7704029, https://www.ncbi.nlm.nih.gov/pubmed/10619715
Xrefs

MESH:C538348

MIM:609284

Synonyms

autosomal recessive congenital myopathy 4B [EXACT]

NEM1 [EXACT]

nemaline myopathy 1 [EXACT]

nemaline myopathy 1, autosomal dominant or recessive [EXACT]

Parent Relationships

is_a congenital myopathy

is_a autosomal recessive disease

Subclass Logical Relationships

existence starts during some Childhood onset

existence starts during some Infantile onset

has material basis in some autosomal recessive inheritance

has symptom some muscle weakness

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