| Metadata | |
|---|---|
| ID | DOID:0111035 |
| Name | CADASIL 1 |
| Definition | A CADASIL characterized by migraine, strokes, and white matter lesions that has_material_basis_in heterozygous mutation in the NOTCH3 gene on chromosome 19p13. https://www.ncbi.nlm.nih.gov/pubmed/10476042, https://www.ncbi.nlm.nih.gov/pubmed/8878478 |
| Xrefs | |
| Synonyms |
autosomal dominant cerebral arteriopathy with subcortical infarcts and leukoencephalopathy type 1 [EXACT] |
| Parent Relationships |
is_a autosomal dominant disease is_a CADASIL |
| Subclass Logical Relationships |
has material basis in some autosomal dominant inheritance |