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Metadata
ID	DOID:0111980
Name	immunodeficiency 64
Definition	A T cell, B cell, and NK cell deficiency characterized by variably decreased numbers of T cells, lesser deficiencies of B and NK cells, decreased phosphorylation of the extracellular-signal-regulated serine kinase ERK in T and B cells, and onset in early childhood of recurrent bacterial, viral, and fungal infections that has_material_basis_in homozygous or compound heterozygous mutation in the RASGRP1 gene on chromosome 15q14. https://pubmed.ncbi.nlm.nih.gov/29282224/, https://pubmed.ncbi.nlm.nih.gov/29155103/, https://pubmed.ncbi.nlm.nih.gov/27776107/
Xrefs	MIM:618534
Synonyms	IMD64 [EXACT]
Parent Relationships	is_a T cell, B cell, and NK cell deficiency is_a autosomal recessive disease
Subclass Logical Relationships	has material basis in some autosomal recessive inheritance