| Metadata | |
|---|---|
| ID | DOID:10923 |
| Name | sickle cell anemia |
| Definition | A sickle cell disease that is characterized by the replacement of both of the beta-globin subunits in hemoglobin with hemoglobin S, resulting in a low number of red blood cells, repeated infections, and periodic episodes of pain. https://en.wikipedia.org/wiki/Sickle_cell_disease, https://ghr.nlm.nih.gov/condition/sickle-cell-disease, https://www.nhlbi.nih.gov/health-topics/sickle-cell-disease |
| Xrefs |
SNOMEDCT_US_2025_04_25:127040003 |
| Alternateids |
DOID:12924 DOID:13024 |
| Subsets |
DO_rare_slim NCIthesaurus |
| Synonyms |
drepanocytosis [EXACT] haemoglobin SC disease [EXACT] Hb SC disease [EXACT] Hb-S/Hb-C disease [EXACT] Hb-SS disease without crisis [EXACT] HbSS disease [EXACT] Hemoglobin S disease without crisis [EXACT] hemoglobin SC disease [EXACT] homozygous sickle cell disease [EXACT] sickle cell anaemia [EXACT] Sickle-cell/Hb-C disease without crisis [EXACT] |
| Parent Relationships |
is_a anemia is_a autosomal recessive disease is_a sickle cell disease |
| Subclass Logical Relationships |
has material basis in some autosomal recessive inheritance has material basis in some erythrocyte |