| Metadata | |
|---|---|
| ID | DOID:12217 |
| Name | Lewy body dementia |
| Definition | A dementia that is characterized by the development of abnormal proteinaceous (alpha-synuclein) cytoplasmic inclusions, called Lewy bodies, throughout the brain that results in progressive decline in mental abilities that has_material_basis_in accumulation of alpha-synuclein, SCNA, (protein). The causal mutation might be in SCNA or SCNB or some other gene(s) but the end result is always accumulation of SCNA in Lewy bodies. http://en.wikipedia.org/wiki/Dementia_with_Lewy_bodies, http://www.mayoclinic.org/diseases-conditions/lewy-body-dementia/basics/definition/CON-20025038 |
| Xrefs |
SNOMEDCT_US_2023_03_01:192808003 |
| Subsets |
DO_rare_slim NCIthesaurus |
| Synonyms |
Dementia with Lewy bodies [EXACT] Diffuse Lewy body disease [EXACT] Lewy body disease [EXACT] Senile dementia of the Lewy body type [EXACT] |
| Parent Relationships |
is_a dementia |