| Metadata | |
|---|---|
| ID | DOID:14482 |
| Name | pemphigoid gestationis |
| Definition | A pemphigoid that is characterized by erythematous papules, vesicles, and plaques around the trunk and extremities that develop during pregnancy, particularly during the second and third trimesters, has_symptom pruritis, and has_material_basis_in autoantibodies to the basement membrane, which triggers a complement cascade and attracts eosinophils to the subepidermis. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3062810/ |
| Xrefs |
SNOMEDCT_US_2023_03_01:86081009 |
| Subsets |
NCIthesaurus |
| Synonyms |
Gestational herpes [EXACT] herpes gestationis [EXACT] |
| Parent Relationships |
is_a primary immunodeficiency disease is_a pemphigoid |
| Subclass Logical Relationships |
has phenotype some Abnormal circulating immunoglobulin concentration and disease has location some (zone of skin and connective tissue) |