| Metadata | |
|---|---|
| ID | DOID:3652 |
| Name | Leigh disease |
| Definition | A cytochrome-c oxidase deficiency disease characterized by progressive loss of mental and movement abilities. Symptoms usually begin between ages of three months and two years and include loss of appetite, vomiting, irritability and seizure activity. https://rarediseases.org/rare-diseases/cytochrome-c-oxidase-deficiency/, http://ghr.nlm.nih.gov/condition/leigh-syndrome, http://en.wikipedia.org/wiki/Leigh%27s_disease, https://rarediseases.org/rare-diseases/leigh-syndrome/ |
| Xrefs |
SNOMEDCT_US_2023_03_01:29570005 |
| Subsets |
DO_FlyBase_slim DO_rare_slim NCIthesaurus |
| Synonyms |
Infantile necrotizing encephalomyelopathy [EXACT] juvenile subacute necrotizing encephalomyelopathy [EXACT] Leigh syndrome [EXACT] subacute necrotizing encephalomyelopathy [RELATED] |
| Parent Relationships | |
| Subclass Logical Relationships |
has symptom some irritability has symptom some seizure has symptom some loss of appetite has symptom some vomiting |