| Metadata | |
|---|---|
| ID | DOID:4252 |
| Name | Alexander disease |
| Definition | A leukodystrophy that is characterized by the destruction of white matter and the formation of Rosenthal fibers consisting of abnormal clumps of protein that accumulate in astrocytes. http://www.omim.org/entry/203450, http://www.ninds.nih.gov/disorders/alexander_disease/alexander_disease.htm, http://www.rarediseases.org/rare-disease-information/rare-diseases/byID/56/viewAbstract, http://en.wikipedia.org/wiki/Alexander_disease |
| Xrefs |
SNOMEDCT_US_2023_03_01:81854007 |
| SKOS |
exactMatch MESH:D038261 |
| Subsets |
DO_FlyBase_slim DO_rare_slim NCIthesaurus |
| Synonyms |
Alexander's disease [EXACT] |
| Parent Relationships |
is_a autosomal dominant disease is_a leukodystrophy |
| Subclass Logical Relationships |
has material basis in some autosomal dominant inheritance |