| Metadata | |
|---|---|
| ID | DOID:5688 |
| Name | Werner syndrome |
| Definition | A progeroid syndrome characterized by premature aging and age-related phenotypes such as atherosclerosis, arteriosclerosis, cataracts, osteoporosis, soft tissue calcification, premature thinning, graying, and loss of hair, as well as a high incidence of some types of cancers and that has_material_basis_in mutations in the WRN gene, on chromosome 8. https://en.wikipedia.org/wiki/Werner_syndrome, https://www.ncbi.nlm.nih.gov/pubmed/15946710, https://www.ncbi.nlm.nih.gov/pubmed/9288107 |
| Xrefs |
SNOMEDCT_US_2023_03_01:51626007 |
| Subsets |
DO_FlyBase_slim DO_rare_slim NCIthesaurus |
| Synonyms |
adult premature ageing syndrome [EXACT] adult progeria [EXACT] Werner's syndrome [EXACT] WS [EXACT] |
| Parent Relationships |
is_a progeroid syndrome |