| Metadata | |
|---|---|
| ID | DOID:6657 |
| Name | breast large cell neuroendocrine carcinoma |
| Definition | A breast carcinoma that is characterized by large cell size, polygonal shape, low nuclear-cytoplasmic ratio, finely granular eosinophilic cytoplasm, occasionally prominent nucleoli, peripheral palisading, mitosis, and necrosis and in which greater than 50% of the tumor cells are positive for neuroendocrine markers (NSE, chromogranin A, synaptophysin). https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4608661/ |
| Xrefs | |
| Subsets |
NCIthesaurus |
| Parent Relationships |
is_a breast carcinoma |